The effect of lifestyle on the prevalence of ovarian cancer

Ovarian cancer is the fifth most important cause of death in women due to cancer. Ovariancancer has the highest mortality rate among female cancers, i.e. cancer of the uterus, cervix andovaries. In ۲۰۱۷, about ۲۲,۴۴۰ women are expected to be diagnosed with ovarian cancer, andabout ۱۴,۰۸۰ people are expected to die from this disease. Having one of the risk factors forovarian cancer or even a number of them means getting It is not a disease, and some peoplewith it may have no known risk factors. A risk factor is anything that increases the likelihoodof developing a disease such as cancer. Different cancers have different risk factors, some ofwhich are modifiable, such as smoking, and others, such as a person's age or family history.Ovarian Cancer Risk Factors Aging: The risk of ovarian cancer in women under ۴۰ is rare andincreases with age. Most ovarian cancers occur after menopause, and half of ovarian cancersoccur in women ۶۳ years and older. Generally, ovarian cancer occurs when the cells inside ornear the ovary undergo DNA mutation. DNA tells the cell what to do. If there is a change andmutation in the DNA, the cell is instructed to grow and multiply rapidly, eventually leading toa cancerous mass. Cancer cells can invade nearby tissues and spread to other parts of the body.Method:The current review by searching in reliable books and useful databases such asScopus, Elsevier, PubMed, Science Direct, Google Scholar, Mag Iran, Iran Dog, Iran Medexin the years ۲۰۱۰ to ۲۰۲۳ with keywords such as lifestyle, nutrition , exercise and physicalactivity, smoking, pregnancy, history of cancer, women's cancers, ovarian cancer and tumorswere done.Findings:The factors that increase the prevalence of ovarian cancer are:Overweight or obesity: Obesity is associated with an increased risk of many cancers. Obesewomen (with a body mass index [BMI] of at least ۳۰) are likely to have a higher risk ofdeveloping ovarian cancer, but not necessarily the most aggressive type. A high degree ofobesity may also negatively affect the overall survival of a woman with ovarian cancer.Late-term pregnancy or no full-term pregnancy: Women who have their first full-termpregnancy after age ۳۵ or never have a full-term pregnancy have a higher risk of ovarian cancer.Use of hormone therapy after menopause: Women who use estrogen alone or with progesteroneafter menopause have a higher risk of developing ovarian cancer than women who have neverused hormones.Having a family history of ovarian cancer, breast cancer, or colon cancer: Ovarian cancercan run in families. Your risk of developing ovarian cancer increases if your mother, sister, ordaughter has (or has had) ovarian cancer. The more relatives you have with ovarian cancer, thegreater the risk. The increased risk of ovarian cancer can also be from the father.Family history: Some other types of cancer, such as colon and breast cancer, are associatedwith an increased risk of ovarian cancer. The reason for this is that these cancers can be causedby genetic mutations of certain genes that cause familial cancer syndrome and increase the riskof ovarian cancer.

Keywords:

Lifestyle , cancer , ovarian cancer