A Case of Plasma Cell Myeloma Presenting with a Huge Ulcerating Breast Mass
Publish Year: 1401
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_JOGCR-8-1_014
تاریخ نمایه سازی: 9 اردیبهشت 1402
Abstract:
Plasma cell myeloma (PCM) of the breast is extremely unusual. It probably constitutes ۰.۷% of extramedullary plasmacytomas, and ۰.۲% of all breast malignancies. Clinically and radiologically, PCM of the breast is indistinguishable from breast carcinoma or other primary breast disorders. Therefore, histomorphological examination with immunohistochemistry are considered as gold standards for its diagnosis in tissue samples. We report a case of a ۳۰-year-old female presented with a progressive huge ulcerating left breast mass, despite chemotherapy. She had a history of an initially misdiagnosed humeral lytic lesion, and recurrent lytic boney lesions for the past ۷ years. Positive CD۱۳۸, CD۵۶ and Kappa immunostaining has confirmed PC differentiation and monoclonality of the tumor cells. Subsequently, PCM of breast was diagnosed and the patient was transferred for chemotherapy and follow-up.
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Authors
Amal Abd El hafez
Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt
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