Angiomyofibroblastoma of Vulva: Case Report with Histomorphological Differential Diagnosis and Review of Literature

Angiomyofibroblastoma (AMF) is a benign mesenchymal neoplasm. They are typically well-circumscribed lesions more commonly occurring in the vulvo-vaginal region of reproductive age females. It is curable by complete excision. They do not have a characteristic clinical and radiological feature. It is an exclusive histopathological diagnosis. However, many mesenchymal neoplasms are predominantly perineal in location, with similar clinical and morphological features and may be confused with angiomyofibroblastoma. We present a ۴۰-year-old married female with ۵.۵ x ۳.۵ x ۲cm left vulval mass, clinically considered to be a Bartholin’s cyst. Magnetic resonance imaging (MRI) was suggestive of infected cystic lesion. Histologically it was an AMF. Histomorphological features are compared with other similar entities occurring in the vulva.

Keywords:

Angiomyofibroblastoma , aggressive angiomyxoma , mesenchymal tumor , vulva