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Cervical ripening: intravaginal misoprostol in compare to intracervical Foley single balloon catheter, a randomized clinical trial

Publish Year: 1402
Type: Journal paper
Language: English
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JR_JOGCR-8-2_003

Index date: 29 April 2023

Cervical ripening: intravaginal misoprostol in compare to intracervical Foley single balloon catheter, a randomized clinical trial abstract

Background: The aim of this study was to compare the efficacy of vaginal misoprostol with Foley balloon catheter for cervical ripening in women with singleton pregnancies and an unfavorable cervix.Methods: Eighty pregnant women with unfavorable cervix were randomly divided in two groups of Foley catheter or misoprostol modes. Cervical ripening in Foley catheter group was done with transcervical Foley catheter 18, and in misoprostol group with 25 μg single dose vaginal misoprostol(The maximum allowed dose for patients was 6 doses.). Bishop score, Apgar score, active phase duration, stage 2 duration and insertion to birth time were the main outcomes.Results: The mean of time between ripening and the active phase in vaginal misoprostol group was significantly shorter than in Foley catheter group (2.32 versus 5.11 hour respectively, P-value = 0.0001). After intervention Bishop score in vaginal misoprostol group was significantly more than Foley catheter group (8.70 versus 6.68 respectively, P-value = 0.0001). Time from insertion to birth in vaginal misoprostol group was 9.54 hours and in Foley catheter group was 12.88 hours (P-value = 0.0001). The hospitalization time in Foley catheter group was significantly more than vaginal misoprostol group (P-value = 0.0001). other outcomes were similar between groups.Conclusion: By the decreasing in the total time from insertion to birth, vaginal misoprostol was more effective than Foley catheter as a cervical ripening method in our study.

Cervical ripening: intravaginal misoprostol in compare to intracervical Foley single balloon catheter, a randomized clinical trial Keywords:

Cervical ripening: intravaginal misoprostol in compare to intracervical Foley single balloon catheter, a randomized clinical trial authors

maryam dehghan

obstetrics and gynecology department, Isfahan university of medical sciences, Isfehan,iran

tajosadat alameh

obstetrics and gynecology department, Isfahan university of medical sciences, Isfahan, Iran

Zahra Allameh

Obstetrics and Gynecology Department, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

zahra Seyed-Hoseini

School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

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