Impact of Serum CA۱۹-۹ Level in Clinico- Pathological and Radiologic Feature of Mature Cystic Teratoma: A Case series

Background & Objective: Ovarian mature cystic teratomas (OMCTS) are one of the most common benign ovarian tumors. Most MCTs can be diagnosed by ultrasonography (us). Due to heterogeneous composition and a variety of appearance, in some non-diagnostic imaging reports it is suggested that we evaluate some tumor markers (CA۱۲۵ and CA۱۹-۹) to complement imaging modalities. According to previous investigation, a single elevated CA ۱۹-۹ is in association with specific radio-pathologic features, such as size, torsion, bronchial glands, fat and teeth components. Here we are presenting three different cases of OMCT with different characteristics. Case Presentation: Case ۱: asymptomatic, non-diagnostic US, single- elevated CA۱۹-۹, smaller than in ۱۰ cm with bronchial glands and fat component. Case ۲: symptomatic, non-diagnostic U.S. normal CA۱۹-۹, larger than ۱۰ cm with torsion and necrosis. Case ۳: symptomatic, diagnostic US, single- elevated CA۱۹-۹, smaller than ۱۰ cm, full of hair and sebaceous material. Computer tomography (CT), in all of our cases was diagnostic based on OMCT. Apologia of pathologic pathway of elevated CA۱۹-۹ in both cases ۱ and ۳ were in agreement with the result of previous investigations. In case ۲, despite its large size and torsion, CA ۱۹-۹ level was low. Conclusion: Single- elevated CA ۱۹-۹ level in OMCTs could impact benign characteristics of this kind of tumor.

Keywords:

Ovarian mature cystic teratoma , CA۱۹_۹ , CA۱۲۵ , Tumor