Investigation of hydrogel nanocomposites and their application in Bone tissue engineering

Hydrogels are ideal for medical applications due to their high biocompatibility, high water absorption and good performance. However, these materials are less used in tissue engineering due to their relatively low mechanical strength. Tissue engineering is recognized as one of the most important disciplines in reconstructive medicine, which combines scaffolding and cell transplantation to develop alternative tissues or promote tissue regeneration. Today, nanocomposite hydrogels with high mechanical properties and some unique properties such as electrical conductivity, antibacterial, antioxidant properties, magnetic response and very suitable response to internal and external stimuli have been introduced as an emerging and creative material. They provide a new opportunity to make hydrogels with excellent properties. Nanocomposite hydrogels can mimic the microenvironment of human bone tissue cell matrix. In this study, we summarize the properties of hydrogels in nanomedicine and the applications of hydrogel nanocomposites in tissue engineering.

Keywords:

Hydrogels , hydrogel nanocomposites , nanomedicine , tissue engineering , Nanoparticle