Investigating the effectiveness of PHR-160 spray in controlling and improving the symptoms of patients with covid-19 - A multicenter, double-blind, randomized clinical trial study

Background: One of the recommended treatment methods for covid-19 is herbal treatments, which, if used, can be used as an effective preventive or supportive treatment in the treatment plan of patients with covid-19. PHR160 spray is combination of cineole, menthol, safran, safranal , crocin that each of these substances effects on respiratory diseases alone.Aim: Investigating the effectiveness of PHR-160 spray, in the treatment of Covid-19.Methods: The present study is a multicenter, double-blind, randomized clinical trial study, which was conducted in 4 medical centers. The study population includes all hospitalized patients with covid-19 who met the study inclusion criteria. The data collection tool was a checklist including: 1- demographic information, 2- vital signs, symptoms, CT scan changes, drug side effects (neural, cardiac and respiratory) at the beginning of admission and from the first to 10th day.Result: There was no significant difference between the intervention and control groups in the study of demographic variables, vital signs, symptoms, CT scan changes, and drug side effects before using PHR-160 spray (P>0.05). Also, after using PHR-160 spray for ten days, there was no significant difference in in the admission to the intensive care unit, and patient mortality in the two groups (P>0.05)Conclusion: Based on the results , PHR-160 spray has no beneficial effects in controlling the symptoms of patients with covid-19 and cannot play a effective role in improving the patient's condition and reducing the complications caused by the disease.Keywords: PHR-160 spray , Covid-19 , treatment , patient.

Investigating the effectiveness of PHR-160 spray in controlling and improving the symptoms of patients with covid-19 - A multicenter, double-blind, randomized clinical trial study Keywords:

Keywords: PHR-160 spray , COVID-19 , treatment , Patient