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Preparation and Evaluation of Electrospun Poly(L-lactide) Scaffold Based on Changing Feeding Rate for Use in Tissue Engineering

Publish Year: 1402
Type: Conference paper
Language: English
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SDNCONF10_032

Index date: 20 July 2023

Preparation and Evaluation of Electrospun Poly(L-lactide) Scaffold Based on Changing Feeding Rate for Use in Tissue Engineering abstract

Bone defects are increasing annually worldwide. Tissue engineering offers a new approach to repairing and regenerating damaged hard tissue by preparing scaffolds. Electrospinning is known as a simple and cost-effective method for fabricating porous bone scaffolds from biocompatible polymers. Electrospun nanofibrous scaffolds can mimic native ECM and thus have found many applications in biomedical engineering. Poly(L-Lactide) is a biodegradable and bioresorbable polymer. In this study, three PLLA-based scaffolds were fabricated via an electrospinning technique at three feed rates of 0.6, 0.7, and 0.8 ml/hr. The results of SEM imaging show that the electrospun scaffold with a feed rate of 0.7 ml/hr has a random, uniform, and bead-free nanostructure and is a suitable candidate for use in hard tissue engineering.

Preparation and Evaluation of Electrospun Poly(L-lactide) Scaffold Based on Changing Feeding Rate for Use in Tissue Engineering Keywords:

Preparation and Evaluation of Electrospun Poly(L-lactide) Scaffold Based on Changing Feeding Rate for Use in Tissue Engineering authors

Hamidreza Fotoukian

Biomedical Engineering Department, Amirkabir university of Technology

Masoumeh Haghbin Nazarpak

New Technologies Research Center (NTRC), Amirkabir university of Technology

Atefeh Solouk

Biomedical Engineering Department, Amirkabir university of Technology

Alireza Nouri

Biomedical Engineering Department, Amirkabir university of Technology