Intradiscal Ozon therapy

BACKGROUND CONTEXTLow back pain with or without radicular leg pain is an extremely common health condition significantlyimpacting patient's activities and quality of life. When conservative management fails, epidural injectionsproviding only temporary relief, are frequently utilized. Intradiscal ozone may offer an alternative to epiduralinjections and further reduce the need for microdiscectomy.PURPOSETo compare the non–inferiority treatment status and clinical outcomes of intradiscal ozone withmicrodiscectomy and discectomy in patients with refractory radicular leg pain due to single-level containedlumbar disc herniations.METHODSozone treatment performed as outpatient day surgeries, included a one-time intradiscal injection delivered at aconcentration of ۳۵±۳ μg/cc of oxygen-ozone by a calibrated delivery system. Discectomies performed asopen microdiscectomy inpatient surgeries, were without spinal instrumentation, and not as subtotalmicrodiscectomies.RESULTSIntradiscal ozon treatments resulted in rapid and statistically significant improvements over baseline in leg painand back pain and life style .