Evaluation of asthma improvement after endoscopic sinus surgery in nasal polyposis

Introduction: Asthma is characterized by airway inflammation, airway hyper responsiveness, and reversible airflow limitation. The prevalence of the disease has increased over ۲ decades to approximately ۵ to ۱۰% of the population. The presence of nasal polyposis in asthma patients is associated with increase in asthma severity. We attempted to determine the efficacy of endoscopic sinus surgery in patients with asthma and nasal polyposis. Materials and Methods: We performed a prospective, cross-sectional study from ۲۰۰۱ until ۲۰۰۶. This study included ۵۰ patients with severe persistent asthma and nasal polyposis. The severity of asthma (in NHLBI and NAPP) and FEV۱ before and after endoscopic nasal polypectomy was recorded. We used paired simple T test for comparation of data mean.The gathered data were analyzed with SPSS software. Results: In this study, median ages are ۳۲.۵ ± ۱۴.۳  years. Male to female is ۲.۳ to ۱. All of patients have severe persistent asthma and nasal polyposis. From ۵۰ patients with asthma and nasal polyposis, in ۳۸ cases asthma severity and FEV۱ were improved. (mean of  FEV۱ before endoscopic  sinus polypectomy = ۱.۶۸ L ,  mean of FEV۱ after endoscopic sinus polypectomy = ۲.۵۲ L).  Conclusion: Opening of upper airway and improvement of breathing through sinus endoscopy induce betterment of asthma severity, though the possibility of nasal polyposis should be investigated and treatment with endoscopic sinus surgery planned accordingly.

Keywords:

Asthma , Nasal polyposis , Sinus endoscopy