Evaluation of Effect of Preoperative Oral Carbohydrate on the Perioperative Agitation in Pediatrics Undergoing Elective Herniorrhaphy; A Doubl-Blind Randomized Clinical Trial

Background The aim of this study was to evaluate the effect of preoperative oral carbohydrate on the perioperative agitation in pediatrics with elective herniorrhaphy. Materials and Methods In this randomized clinical trial study, ۱۲۰ pediatrics, ۶ months to ۱۰ years-old who underwent elective herniorrhaphy were admitted. Sixty pediatrics in the intervention group received ۵ ml/kg of ۲۰% dextrose solution manufactured by Samen Company as carbohydrate beverage exactly ۲ hours before surgery and the control group (n=۶۰) received distilled water. The perioperative agitation score was calculated as follows. Score ۱: quiet, silent child, score ۲: mild but agitated, score ۳: medium aggression, and score ۴: severe agitation measured before surgery, at recovery, ۵, ۱۵ and ۳۰ minutes after intervention. Also, the incidence of nausea and vomiting was recorded in each group. Results Of the ۶۰ pediatrics in the intervention group, ۵۴ patients were quiet and silent at the time of entry into the operating room, and ۶ patients had mild agitation; in the control group, ۷ patients were quiet and silent, ۴۱ patients were mild but agitated, and ۱۲ were moderate. There was a significant difference in agitation between the two groups (P = ۰.۰۰۱). Five minutes after surgery, ۵۴ patients scored ۱, ۶ patients scored ۲ in the control group, ۲۷ patients scored ۱ and ۳۳ patients scored ۲. There was a significant difference between agitations of children ۵ minutes after intervention in the two groups. Conclusion Five ml/kg of ۲۰% dextrose solution as carbohydrate beverage exactly ۲ hours before anesthesia may lead to parental satisfaction and improvement in positive behavior of pediatrics at anesthesia induction and wake up from anesthesia.

Keywords:

Carbohydrates , Children , Herniorrhaphy , Preoperative fasting , Perioperative agitation