Ethanol Concentration and Its Correlation with CNS Suppressor Drugs in Postmortem Subjects

Background: Many studies have been done in order to interpret correctly the results of ethanol analysis and its related problems. Unfortunately, it was not easy to determine BAC rate, due to postmortem different conditions or personal and clinical differences in metabolism and excretion of ethanol. The time between death and autopsy, the environmental conditions (temperature and humidity) are important factors to be taken into account. Concentration of ethanol in vitreous humor depends on the person’s age, drinking experience and degree of tolerance development. Methods: In this study, concentration of ethanol in vitreous humor was assessed in ۱۰۰ cases with consumption of CNS suppressor drugs that were detected in urine and tissue. Results: The toxicity of ethanol is often considerably enhanced by the concomitant use of other drugs with their site of action in the brain especially opiates, antidepressants and some sedative hypnotics. Conclusion:  Death occurs in low concentration of alcohol consumed simultaneously with CNS suppressor drugs.

Keywords:

Autopsy , Central Nervous System Agents , Ethanol , Vitreous Body