Sulfonylbis(۱,۴-phenylene)bissulfamic acid (SPSA): Introduction of an efficient and reusable catalyst for the synthesis of bis(indolyl)methanes
Publish place: Asian Journal of Green Chmistry، Vol: 1، Issue: 2
Publish Year: 1396
نوع سند: مقاله ژورنالی
زبان: English
View: 61
This Paper With 11 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_AJGC-1-2_003
تاریخ نمایه سازی: 11 شهریور 1402
Abstract:
A simple, efficient and convenient route is described for the synthesis of bis-indolyl methanes by using recyclable catalyst sulfonylbis(۱,۴phenylene)bissulfamic acid (SPSA). In this procedure, we synthesize a bis-indolyl methane derivative via the three component reactions of two equivalent indoles with one equivalent of various aromatic aldehydes in the presence of ۱۰ mol% SBSA as a heterogeneous catalyst under solvent-free conditions at ۱۱۰ °C for the convinced reaction times (۳۰–۶۰ min). The advantages of this protocol towards the synthesis of bis-indolyl methane derivatives are: I) use of solvent-free conditions, II) inexpensive catalyst, III) using commercially available precursors, d) reusability of SBSA up to several cycles without much loss in reactivity, IV) simple work-up, V) high yields of pure products, VI) short reaction times. The structure of all bis(indolyl)methane derivatives were confirmed by melting point, FT-IR, ۱H NMR spectra and were compared with reliable references.
Keywords:
Sulfonylbis(۱ , ۴-phenylene)bissulfamic acid (SPSA) Bis-indolyl methanes Aldehyde Indoles Multi-component reactions
Authors
Masoud Mohammadi Zeydi
Department of Organic Chemistry, Faculty of Sciences, University of Guilan, Rasht, Iran
Nosrat O Allah Mahmoodi
Department of Organic Chemistry, Faculty of Sciences, University of Guilan, Rasht, Iran
Ghorban Ardeshiri Terogeni
Department of Organic Chemistry, Faculty of Sciences, University of Guilan, Rasht, Iran
مراجع و منابع این Paper:
لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :