سیویلیکا را در شبکه های اجتماعی دنبال نمایید.

Glycerol-Water Green Solvent for Bioactive Metabolites Extraction from Ranunculus arvensis and Extraction Optimization by Response Surface Methodology

Publish Year: 1402
Type: Journal paper
Language: English
View: 137

This Paper With 17 Page And PDF Format Ready To Download

Export:

Link to this Paper:

Document National Code:

JR_AJGC-7-4_007

Index date: 2 September 2023

Glycerol-Water Green Solvent for Bioactive Metabolites Extraction from Ranunculus arvensis and Extraction Optimization by Response Surface Methodology abstract

Ranunculus arvensis L. is a medicinal herb traditionally used for various purposes. The objective of the present research project was to find an effective and green method for obtaining bioactive natural products from it. Aqueous glycerol was employed as a green extracting medium, and the bioactive compounds were estimated as total flavonoid content (TFC) total phenolic content (TPC), antioxidant activity, and metal chelating activity (MCA). Response surface methodology (RSM) was applied to optimize the extraction process with temperature, time, and solvent (glycerol) concentration as input factors. The optimized conditions were 30 °C, 30 min, and 70% glycerol concentration at which the responses were TPC 7.15 mg gallic acid equivalents/g DW (dry weight), TFC 14.8 mg rutin equivalents/g DW, antioxidant 59.55%, and MCA 49.14%. The model was strongly supported by the validation study. The explored extraction process for bioactive natural products from R. arvensis is predictably applicable. Hence, 70% aqueous glycerol at almost room temperature and a minimum duration of 30 min can allow optimum extraction of phenolics, flavonoids, antioxidants, and metal chelators from R. arvensis.

Glycerol-Water Green Solvent for Bioactive Metabolites Extraction from Ranunculus arvensis and Extraction Optimization by Response Surface Methodology Keywords:

Ranunculus arvensis Polyphenols Glycerol , water green solvent Extraction optimization Response surface methodology

Glycerol-Water Green Solvent for Bioactive Metabolites Extraction from Ranunculus arvensis and Extraction Optimization by Response Surface Methodology authors

Sana Anayat

Department of Chemistry, Forman Christian College (A Chartered University), Lahore, Pakistan

Dildar Ahmed

Department of Chemistry, Forman Christian College (A Chartered University), Lahore, Pakistan

Mahnoor Anis

Department of Chemistry, Forman Christian College (A Chartered University), Lahore, Pakistan

Nida Anis

Department of Chemistry, Forman Christian College (A Chartered University), Lahore, Pakistan

مراجع و منابع این Paper:

لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :
. Van Wyk B.E., Wink M. Medicinal plants of the world., ...
نمایش کامل مراجع