Synthesis of Poly-substituted Hydroquinolines Employing Lactic Acid as a Robust Catalyst through the Diastereoselective, One-pot Eight-component Reaction
Publish place: Organic Chemistry Research، Vol: 5، Issue: 2
Publish Year: 1398
نوع سند: مقاله ژورنالی
زبان: English
View: 78
This Paper With 8 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_ORGC-5-2_012
تاریخ نمایه سازی: 3 مهر 1402
Abstract:
With the aim of developing an efficient and eco-friendly method for a diastereoselective synthesis of dispiro[tetrahydroquinoline-bis(۲,۲-dimethyl[۱,۳] dioxane-۴,۶-dione)] derivatives, a one-pot pseudo-eight-components reaction between arylamines, aromatic aldehydes and Meldrum’s acid has occurred in the presence of lactic acid as catalyst. The salient aspects of this protocol are, operational simplicity, facile product separation, a cheap and eco-friendly catalyst, clean reaction conditions, absence of any hazardous organic solvent and moderate to high yields.
Keywords:
Authors
Fatemeh Noori Sadeh
Department of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, P.O. Box ۹۸۱۳۵-۶۷۴, Zahedan, Iran
Mojtaba Lashkari
Faculty of Sciences, Velayat University, Iranshahr, Iran
Nourallah Hazeri
Department of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, Zahedan ۹۸۱۳۵-۶۷۴, Iran
Maryam Fatahpour
Department of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, P.O. Box ۹۸۱۳۵-۶۷۴, Zahedan, Iran
Malek Taher Maghsoodlou
Department of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, P.O. Box ۹۸۱۳۵-۶۷۴, Zahedan, Iran