One-pot Synthesis of Some Novel ۲-[(Z)-۱-(Aryl)]-۶,۷-dihydro-۲H-istohiazolo[۲,۳-a]pyrimidine-۳(۵H)-one Derivatives
Publish place: Organic Chemistry Research، Vol: 4، Issue: 1
Publish Year: 1397
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_ORGC-4-1_009
تاریخ نمایه سازی: 3 مهر 1402
Abstract:
Reaction of ۳,۴,۵,۶-tetrahydro-۲-pyrimidinethiol, prepared by cyclocondensation reaction of ۱,۳-diamino propane ۱ and carbon disulfide, with ethyl chloroacetate and substituted aromatic aldehydes in the presence of sodium acetate and acetic acid gave ۲-[(Z)-۱-(aryl)]-۶,۷-dihydro-۲H-isothiazolo[۲,۳-a]pyrimidine-۳(۵H)-one derivatives ۳(a-j) in good yields. ۱H-NMR spectroscopy, and elemental analysis were used for identification of these compounds.
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Authors
Akbar Mobinikhaledi
Chemistry Department, Arak University, Dr. Beheshti Ave, Arak, Iran
Naser Foroughifar
Faculty of Chemistry, Tehran North Branch, Islamic Azad University, Tehran, Iran
Hassan Moghanian
Department of Chemistry, Islamic Azad University-Dezful Branch, Dezful, Iran.
Hamid Reza Jaberi
Department of Chemistry, Faculty of Science, Arak University, Arak, Iran