Synthesis of Furo[۲,۳-d]pyrimidine-۲,۴(۱H,۳H)-diones From Alcohols Using T۳P/DMSO
Publish place: Organic Chemistry Research، Vol: 3، Issue: 1
Publish Year: 1396
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_ORGC-3-1_005
تاریخ نمایه سازی: 3 مهر 1402
Abstract:
T۳P/DMSO is shown to be an effective and mild reagent for the one-pot synthesis of furo[۲,۳-d]pyrimidine-۲,۴(۱H,۳H)-diones from a variety of alcohols. Alcohols are oxidized in situ to aldehydes under mild conditions, which undergo a three-component reaction with N,N'-dimethylbarbituric acid and various isocyanides to afford furo[۲,۳-d]pyrimidine-۲,۴(۱H,۳H)-diones in good yields.
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Authors
Ebrahim Soleimani
Department of Chemistry, Razi University, Kermanshah ۶۷۱۴۹-۶۷۳۴۶, Iran.
Mohammad Mehdi Khodaei
Department of Chemistry, Razi University, Kermanshah ۶۷۱۴۹-۶۷۳۴۶, Iran.
Hossein Yazdani
Department of Chemistry, Razi University, Kermanshah ۶۷۱۴۹-۶۷۳۴۶, Iran.
Jafar Mohammad Nejhad
Department of Chemistry, Shahr-e-Qods Branch, Islamic Azad University, Tehran, Iran