Antioxidant, antineurodegenerative, anticancer, and antimicrobial activities of caffeine and its derivatives: micro and nano aspects
Publish place: Micro Nano Bio Aspects، Vol: 2، Issue: 3
Publish Year: 1402
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_MNBA-2-3_005
تاریخ نمایه سازی: 2 آبان 1402
Abstract:
There are therapeutic and side effects of caffeine. Caffeine as a psychoactive compound can impact the function of the nervous system and lead to alterations in cognitive and physical performance. Therefore, caffeine can be consumed as a nutritional ergogenic aid. However, several side effects including headache and nervousness have been recognized in doses of more than ۴۰۰ mg daily. In addition, this alkaloid has shown antioxidant, antineurodegenerative, anticancer, and antimicrobial activities. In the case of antioxidant activity, caffeine showed anti-cataract potential and delayed the onset of lens clouding. Recently, for increasing therapeutic effects, numerous organic and inorganic nanomaterials such as cosmeceutical nanogels, lipid-based nanocarrier, hydrogels, protein-polysaccharide nanoconjugates, and cyclodextrin have been employed. This article has tried to cover the antioxidant, antineurodegenerative, anticancer, and antimicrobial activities of caffeine based on recent investigations.
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Authors
Shadieh Mohammadi
Environmental Health Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Kurdistan, Iran
Maral Maghsoudloo
Louisiana Tech University, Collage of Engineering & Science, Ruston, Louisiana, USA
Mohammad Maroufi
Department of Biological Science, Faculty of Science, University of Kurdistan, Sanandaj, Kurdistan, Iran