miRNAs and rheumatoid arthritis: new update in expression pattern and pathogenicity
Publish place: Rheumatology Research، Vol: 6، Issue: 3
Publish Year: 1400
Type: Journal paper
Language: English
View: 133
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Document National Code:
JR_RHRE-6-3_001
Index date: 15 November 2023
miRNAs and rheumatoid arthritis: new update in expression pattern and pathogenicity abstract
Rheumatoid arthritis (RA) is a polygenic autoimmune disease characterized by systemic inflammation and disability of joints. Early diagnosis and treatment could prevent diseases in RA patients from becoming severe. miRNAs are small, non-coding RNA that regulate the post-transcriptional level of gene expression. miRNAs play important roles in gene expression and pathogenicity of autoimmune diseasesas well as RA. Properly using miRNAs regulation potential and detecting different expression patterns andtheir functions could facilitate and manage effective therapeuticinterventions in RA patients. Herein, we discuss miRNAs as a therapeutic agent in RA patients.
miRNAs and rheumatoid arthritis: new update in expression pattern and pathogenicity Keywords:
miRNAs and rheumatoid arthritis: new update in expression pattern and pathogenicity authors
Hamidreza Ebrahimiyan
۱. Department of Stem Cells and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran ۲. Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran
Arman Ahmadzadeh
Department of Rheumatology, Loghman Hakim Hospital, Shahid Beheshti, University of Medical Sciences, Tehran, Iran