Hypercholesterolemia and insulin resistance associated with ovarian remnant syndrome in a diabetic dog: case report
Publish place: Veterinary Research Forum، Vol: 13، Issue: 2
Publish Year: 1401
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_VRFAN-13-2_019
تاریخ نمایه سازی: 25 آبان 1402
Abstract:
A ۹-year-old spayed female Terrier dog was evaluated for lethargy, anorexia, polyuria, polydipsia and dysuria. The dog had been diagnosed with diabetes mellitus about ۶ months ago and received subcutaneous doses of insulin. The patient showed insulin resistance and severe persistent fasting hyperglycemia in the face of high-dose insulin treatment, hyper-cholesterolemia and urinary tract infection. After a complete evaluation, the dog was diagnosed with a polycystic ovary and a cystic uterine remnant during an exploratory celiotomy. The polycystic ovary and cystic uterine remnant were removed and submitted for histopathological evaluation. Two weeks after surgery the blood glucose level and one month later serum cholesterol level were controlled, using a low level of insulin therapy (۰.۲۵ IU kg-۱ Neutral Protamine Hagedorn (NPH) insulin, every ۱۲ hr). In the present study, the clinical and laboratory results showed that ovarian remnant syndrome as an infrequently encountered condition in dog was related to some metabolic disorders such as insulin resistance, uncontrolled hyperglycemia, dyslipidemia and also recurrence urinary tract infection. To the best of authors’ knowledge, no reports of hypercholesterolemia in dog have been made before as a complication of ovarian remnant syndrome.
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Authors
Hamidreza Moosavian
Department of Clinical Pathology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
Mahsa Fazli
Department of Biology, Faculty of Basic Science, Islamic Azad University, Tehran, Iran
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