Central Composite design (CCD) optimization and characterization ofremoval of Entacapone drug using copper zinc cobalt ferrite nanoparticlesmodified by cetyltrimethylammonium bromide (Cu۰.۳Zn۰.۳Co۰.۴Fe۲O۴@CTAB)nanoparticles and Adsorption Characterization

Copper zinc cobalt ferrite nanoparticles modified by cetyltrimethylammonium bromide(Cu۰.۳Zn۰.۳Co۰.۴Fe۲O۴@CTAB NPs) are used as an efficient adsorbent to remove Entacapone (En)drug from aqueous solutions. The characterization of adsorbent is investigated by field emissionscanning electron microscopy (FE-SEM), X-ray diffraction (XRD), Fourier transform infrared(FT-IR) spectroscopy, energy dispersive X-ray spectroscopy (EDX), and the vibrating samplemagnetometer (VSM) technique. To optimize the effective factors, response surface methodology(RSM) through using Central Composite design (CCD) is applied. By proper running of theDesirability function option in MINITAB software, the optimum conditions were found as pH ۳.۰,adsorbent mass (m) ۱۰ mg, and initial dye concentration (Cd) of ۷۷ mg L−۱. Isotherm studies of theadsorption process are carried out where the Langmuir isotherm shows the maximum monolayercapacity (qmax) is ۲۲۴ mg g−۱. The kinetic studies including pseudo-first-order, pseudo-secondorder,and intra-particle diffusion models indicate that the pseudo-second-order kinetic modeldescribes better the adsorption kinetic behavior. This study shows thatCu۰.۳Zn۰.۳Co۰.۴Fe۲O۴@CTAB NPs have excellent potential for the removal of Entacapone (En)drug from an aqueous solution.

Keywords:

Adsorption , Mixed Magnetic Oxides Nanoparticles , Removal , Drug , Response SurfaceMethodology