Nanomagnetic Schiff Base Complex of Copper(II): Synthesis,Characterizations, and Its Catalytic Application in synthesis of ۵-substituted-۱H-tetrazole derivatives

Homogeneous catalysts, which have been widely utilized to catalyze chemical processes, havelow recoverability, reusability, and stability [۱]. To circumvent these constraints, heterogeneouscatalysts that are more efficient and environmentally benign are being investigated [۲-۳]. Severalinvestigations have been carried out in which supported precious metals, such as palladium, goldand silver, were utilized as catalysts for the click functionalization of aryl nitriles to theircorresponding ۵-substituted-۱H-tetrazoles (RCN۴H). Generally, the immobilization of transitionmetals on high-surface-area materials, such as nanomaterials, has been documented [۴]. Herein,Fe۳O۴ is used as a support material for the ACAC functionalities. Afterwards, the correspondingCu(II) Schiff base complex was synthesized using the template approach and, then, it was appliedas a promoter to assist the sustainable synthesis of ۵-substituted-۱H-tetrazole derivatives in PEG-۴۰۰ as a greener alternative for the traditional solvents (Scheme ۱)

Keywords:

Magnetic Nanoparticles , ۵-substituted-۱H-tetrazoles Immobilized Copper Complex