Facile synthesis of muscovite-supported metal-organic framework(MUS@MOF) composite forpotential antibacterial activity

Uncontrollable bleeding has been considered one of the leading causes of death around theworld. Thus, the development of new wound dressing materials with enhanced hemostaticproperties is quite necessary. Meanwhile, bacterial infection is a crucial issue that can impairwound healing, as the blood clot can become a hotbed of bacterial growth and cause woundinflammation. So, today researchers focus on new materials and composites that enhanced theantibacterial properties of wound dressing.Metal-organic frameworks (MOFs), as relativelyemerging crystalline nanoporous materials, have been gaining many interests thanks to theirlarge specific surface area, high porosity, adjustable pore size, versatile functionality, andenriched host-guest chemistry. Among the MOFs, Cu-based MOF with antibacterial propertieshas been developed, recently [۱].On the other hand, Muscovite (also known as common mica,isinglass, or potash mica) is a hydrated phyllosilicate mineral of aluminum and potassium.According to the good properties of Muscovite and MOFs, we intend to synthesize andcharacterize this composite for potential application in wound dressing.Crystalline structure,chemical structure and bounds, morphological, and elemental analysis of MUS@MOFnanocomposite were carried out by X-Ray diffraction (XRD), Fourier transform infraredspectroscopy (FTIR), field-emission scanning electron microscopy (FE-SEM) and EnergyDispersive X-ray Spectroscopy (EDS), respectively. The analysis of the XRD and FTIR resultsconfirmed the successful synthesis of MUS@MOF nanocomposite. The FTIR revealed that theMOF interacted with the muscovite surface.TheEDS analysis also exhibited the presence of Cu,Si, Al, O, and C atoms, confirming the successful synthesis of MUS@MOF nanocomposite.FESEMimages showed that MOFs with nanometer particle size (minimum ۱۸.۳۸ nm, maximum۳۹.۶۳ nm) have been well synthesized on two-dimensional (۲D) muscovite sheets.

Keywords:

Metal-organic framework , muscovite , antibacterial