An Investigation of the Clinico-histopathologic Trend of Salivary Gland Tumors in Amir Alam Hospital During ۲۰۱۰- ۲۰۱۹: A Retrospective Study

Background: The incidence and mortality rates of salivary gland tumors have increased according to previous evidence. No study has so far focused on the trend of clinical and histopathologic patterns of salivary gland tumors in Iran. Therefore, the aim was to investigate the incidence and clinicohistopathologic trend of salivary gland tumors in a retrospective, cross-sectional, institutional study from ۲۰۱۰-۲۰۱۹ in Amir Alam hospital. Methods: The archived medical records were collected from patients with the histopathologic diagnosis of benign and malignant salivary gland tumors from Amir Alam hospital, Tehran during (April-April) ۲۰۱۰- ۲۰۱۹. Demographic data and histopathologic features, including tumor size, lymph node involvement, vascular invasion, perineural involvement, and histopathologic differentiation were retrieved, and the samples were categorized and reviewed based on the new classification of head and neck tumors. Finally, the frequencies of characteristics were determined and expressed as numbers (percentage values). Results: Of ۱۲۰۳ salivary gland tumors, ۷۷.۶% and ۲۲.۴% were benign and malignant, respectively. The incidence of benign tumors was increased from ۳۷ (۲۲.۲%) in ۲۰۱۰ to ۱۷۸ (۳۶۴.۹%) in ۲۰۱۹. In the collection of the total samples, the incidence of malignant tumors was relatively steady from ۲۳ (۱۳.۸%) samples in ۲۰۱۰ to ۲۷ (۵۵.۳۵%) in ۲۰۱۹. However, an increase in the incidence of tumors with low-grade differentiation was found from ۱۲.۵% in ۲۰۱۰ to ۸۰% in ۲۰۱۹. Conclusions: The incidence of benign and malignant salivary tumors with a higher degree of malignancy had an increasing trend in Amir Alam hospital during ۲۰۱۰-۲۰۱۹.

Keywords:

Diseases , Epidemiology , Salivary glands , Trends