Prevalence and antibiotic resistance of uropathogens in children with urinary tract infections referring to Abuzar hospital in Ahvaz

Publish Year: 1400
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_JCBIOR-2-3_003

تاریخ نمایه سازی: 14 آذر 1402

Abstract:

Urinary tract infection (UTI) is a prevalent disease among children. This study is an attempt to find the bacterial agents of UTI and antibiotic resistance in children. A descriptive cross-sectional study was carried out on ۱۳۱۶ clinical samples of children at Abuzar Hospital in Ahvaz that had positive urine culture. The strains were determined through biochemical tests and differential culture media. The pattern of antibiotic resistance of the studied strains was determined by the disk diffusion method. Out of the ۱۳۱۶ children surveyed, ۸۲۱ were girls and ۴۹۵ were boys. The most isolated strains from urine cultures were Escherichia coli (۵۷.۵۲%) followed by Enterococcus (۱۲.۱۵%). E. coli isolates demonstrated the highest resistance to ampicillin (۵۷.۰۶%) and amikacin was recognized as the most effective antibiotic with a sensitivity of ۹۱.۹۴%. E. coli was the most common causative agent of UTI in children. Amikacin was recognized as the appropriate choice against urinary tract pathogens. Because, in different regions and over time, the frequency distribution of antibiotic resistance varies, it is recommended to carry out periodic monitoring of antibiotic resistance for infection control.

Authors

Sousan Akrami

Department of Microbiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Seyede Mahla Mavalizade

Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran- Department of Laboratory Sciences, School of Allied Medical Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Mehran Varnaseri Ghandali

۴Department of Infectious Diseases, Razi Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran

Aram Asareh Zadegan Dezfuli

Department of Microbiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran