Effect of phenylephrine spray on closed reduction of nasal fractures in patients under general anesthesia
Publish place: Journal of Surgery and Trauma، Vol: 5، Issue: 3
Publish Year: 1396
نوع سند: مقاله ژورنالی
زبان: English
View: 51
This Paper With 6 Page And PDF Format Ready To Download
- Certificate
- من نویسنده این مقاله هستم
استخراج به نرم افزارهای پژوهشی:
شناسه ملی سند علمی:
JR_JSTR-5-3_003
تاریخ نمایه سازی: 5 دی 1402
Abstract:
Introduction: As the most anterior part of the face, the nose is more prone to trauma than other parts of the face, thereby making it the most common facial fracture site. Closed reduction has long been used as the standard treatment of the nasal fracture, which can be performed outpatiently or inpatiently. Bleeding due to the fracture can be minimized by adopting certain strategies before the realignment of the nasal fracture. One of these strategies is to use phenylephrine spray before surgery. This study aimed to evaluate the effect of phenylephrine spray in closed reduction of nasal fractures.
Methods: A total number of ۲۰۰ patients with nasal fracture – who were admitted to the ENT department of Vali-e-Asr Hospital in ۲۰۱۴ and ۲۰۱۵ – were incorporated in this clinical trial via simple randomization method. The patients were assigned into case and control groups. The case group received phenylephrine spray twice: ۳۰ minutes before the surgery and before anesthesia. The control group did not receive phenylephrine spray. To evaluate the efficiency of the spray, data concerning intraoperative and postoperative bleeding, pain intensity, blood pressure, and the need for tampon in both groups were recorded. The data were compared in the SPSS software version ۱۸ using T-test and Chi-Square test at a confidence level of ۹۵%.
Results: The average age of the participants was ۲۵.۱۲±۱۳.۷۳ years and the majority were men (n=۱۲۷; ۶۳.۵%). The mean systolic pressure of the patients in the case group was significantly higher than that of the patients in the control group (P=۰.۰۲). Furthermore, the bleeding volume during surgery in the cases was significantly lower than that of the controls (P=۰.۰۱). However, postoperative bleeding volume, pain intensity, and the need for tampon were not significantly different in the groups.
Conclusions: By reducing the intraoperative bleeding, phenylephrine spray can play an important role in decreasing the complications caused by surgery. However, it is not recommended for the patients with heart diseases because it increases systolic pressure.
Keywords:
Authors
Mohammad Reza Mofatteh
Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran
Forod Salehi
Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran
Mehran Hosseini
Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran
Mohammad Reza Doostabadi
Instructor of Anatomical Sciences, Birjand University of Medical Sciences, Birjand, Iran
Mohammad Mehdi Hassanzadeh Taheri
Instructor of Anatomical Sciences, Birjand University of Medical Sciences, Birjand, Iran
مراجع و منابع این Paper:
لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :