Repeated Transcranial Direct Current Stimulation (tDCS) on Methamphetamine Craving: A Randomized, Sham-controlled Study
Publish place: Iranian Rehabilitation Journal، Vol: 17، Issue: 4
Publish Year: 1398
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_IRJU-17-4_012
تاریخ نمایه سازی: 5 دی 1402
Abstract:
Objectives: The modulation of the dorsolateral prefrontal cortex (DLPFC) activity enhanced the prospects of substance use disorders rehabilitation, using non-invasive brain stimulation, such as transcranial Direct Current Stimulation (tDCS).
Methods: We carried out a randomized sham-controlled clinical trial to assess the effect of repeated tDCS at DLPFC on drug craving in ۳۰ abstinent male methamphetamine users. The participants underwent ۵ sessions of ۲۰ minutes bilateral real or sham ۲ mA tDCS (anode right/ cathode left) of DLPFC. The Desire for Drug Questionnaire (DDQ) was used for assessing instant craving. The cue-induced craving was rated on a Visual Analog Scale (VAS) after the verbal induction of craving.
Results: The findings of this study indicated that cue-induced craving reduced significantly in tDCS related to sham (P<۰.۰۵), but tDCS did not significantly alter instant craving.
Discussion: The results indicated that repeated bilateral tDCS over DLPFC was not effective in reducing self-report instant craving, but reduced self-reported craving in the craving induction condition.
Keywords:
Authors
Mahsa Rohani Anaraki
Department of Clinical Psychology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Behrouz Dolatshahi
Department of Clinical Psychology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Masoud Nosratabadi
Department of Clinical Psychology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Mohsen Nouri Yalghouzaghaji
Department of Clinical Psychology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
Sajede Rezaei Mashhadi
Department of Clinical Psychology, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.
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