Evaluation of the Antioxidant Effects of Green Tea (Camellia sinensis) on Male Albino Mice poisoned with Thioacetamide

Publish Year: 1394
نوع سند: مقاله ژورنالی
زبان: English
View: 56

This Paper With 10 Page And PDF Format Ready To Download

  • Certificate
  • من نویسنده این مقاله هستم

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این Paper:

شناسه ملی سند علمی:

JR_TBSRJ-0-1_003

تاریخ نمایه سازی: 7 دی 1402

Abstract:

Background & Objectives: Effects of free radicals and reactive oxygen species (ROS) on biological systems have been one of the most important medical concerns. Production of free radicals and ROS is inherent to aerobic life. This study aimed to investigate the antioxidant effects of green tea (camellia sinensis) on male Albino mice poisoned with thioacetamide. Materials and Methods: In this study, thioacetamide was injected intraperitoneally at doses of ۱۰۰ and ۱۵۰ mg/kg. In addition, enzyme activity of catalase (CAT) and glutathione peroxidase (GPx), as well as the concentration of malondialdehyde (MDA) as the main source of antioxidants, were measured in all the study groups. Results: There was a significant increase in the activities of CAT and GPx, while a significant decrease was observed in the level of MDA in the mice receiving combined green tea and thioacetamide compared to the recipients of thioacetamide alone (P<۰.۰۵). Conclusion: According to the results of this study, the antioxidant properties of green tea are associated with the presence of a polyphenol called catechin in this plant.

Authors

Ashraf Sharifi

MSc. Student of Biochemistry, Research & Science Branch, Islamic Azad University of Fars, Iran

Nooshin Naghsh

PhD. of Animal Physiology, Associate Professor and Faculty Member of Islamic Azad University, Falavarjan Branch, Isfahan, Iran

Nematollah Razmi

PhD. of Clinical Biochemistry (Orientation to Cancer), Associate Professor and Faculty Member, Research & Science Branch, Islamic Azad University of Fars, Iran

مراجع و منابع این Paper:

لیست زیر مراجع و منابع استفاده شده در این Paper را نمایش می دهد. این مراجع به صورت کاملا ماشینی و بر اساس هوش مصنوعی استخراج شده اند و لذا ممکن است دارای اشکالاتی باشند که به مرور زمان دقت استخراج این محتوا افزایش می یابد. مراجعی که مقالات مربوط به آنها در سیویلیکا نمایه شده و پیدا شده اند، به خود Paper لینک شده اند :
  • Attaran M, Pasqualotto E, Falcone T, Goldberg JM, Miller KF, ...
  • Pierce JD, Cackler AB, Arnett MG Why should you care ...
  • Halliwell B. Free radicals, reactive oxygen species and human disease: ...
  • Bruck R, Shirin H, Aeed H, Matas Z. Prevention of ...
  • Zaragoza A, Andres D, Sarrion D, Cascales M. Potentiation of ...
  • Arts IC, Hollman PC, Kromhout D. Chocolate as a source ...
  • Nakagawa T, Yokozawa T. Direct scavenging of nitric oxide and ...
  • Zi x, Mukhtar H, Agarwal R. Novel cancer chemopreventive effects ...
  • Frei B, Higdon JV. Antioxidant activity of tea polyphenols in ...
  • Okada K, Wangpoengtrakut C, Tanaka T, Tomoyuki S, Uchida K, ...
  • Babich H, Gold T, Gold R. Mediation of the in ...
  • Bearden MM, Pearson DA, Rein D, Chevaux KA, Carpenter DR, ...
  • Matito C, Mastoraku F, Centelles JJ, Torres JL, Cascante M. ...
  • Aebi H. Catalase in vitro. Method Enzymol. ۱۹۸۴; ۱۰۵:۱۲۱-۶ ...
  • Paglia DE, Valentine WN. Studies on the quantitative and qualitative ...
  • Kei S. Serum lipid peroxide in cerebrovascular disorders determined by ...
  • McCay PB, Lai EK, Poyer JL, Dubose CM. Janzen EC. ...
  • Bagchi K, Puri S. Free radicals and antioxidants in health ...
  • Traystman RJ, Kirsch JR, Koehler RC. Oxygen radical mechanisms of ...
  • Yano CL, Marcondes MC. Cadmium chloride-induced oxidative stress in skeletal ...
  • Halliwell B. Antioxidant characterization methodology and mechanisms. Biochem Pharmacol. ۱۹۹۵; ...
  • Juranek I, Bezek S. Controversy of free radicals hypothesis: Reactive ...
  • Skrzydlewska E, Ostrowska J, Farbiszewski R, Michalak K. Protective effect ...
  • Lotito SB, Fraga CG. Catechins delay lipid oxidation and alpha-tocopherol ...
  • August DA, Landau JA, Caputo D, Hong J, Lee MJ, ...
  • Ohno Y, Wakai K, Genka K, Ohmine K, Kawamura T, ...
  • Li N, Sun Z, Han C, Chen J. The chemopreventive ...
  • Erba D, Riso P, Bordoni A, Foti P, Biagi PL, ...
  • نمایش کامل مراجع