An Update of Pharmacological and Non-pharmacological Therapies for COVID-۱۹ Pandemic Trivia

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نوع سند: مقاله ژورنالی
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تاریخ نمایه سازی: 10 دی 1402

Abstract:

Background: The whole planet is facing one of the scariest pandemic situations in this era. On ۱۱th February, ۲۰۲۰ the World Health Organization announced the name of an unknown disease as COVID-۱۹, which is caused by the ssRNA virus SARS-CoV-۲ (formally recognized as a sister of SARS-CoV and MERS-CoV). The epicenter of this disease is Wuhan, Hubei Province, China. COVID-۱۹ can affect all age groups, but particularly affects immune compromised and aged persons with co-morbid conditions. It is highly contagious disease that involves mild to severe respiratory symptoms along with breathing difficulties.  Objectives: As SARS-CoV-۲ is a new strain of β-coronavirus that spreads from animals to humans via an unknown intermediate host, no vaccines have been developed yet and only supportive treatment is given to the infected patients. The review paper highlights the pharmacological therapy as a supportive treatment given to the COVID-۱۹ patients and non-pharmacological therapeutic approaches for the prevention. Methods: Methods: Authors were surveyed and reviewed numerous articles, magazines, news papers, conference proceedings from different search engines and made the review successful. Results: Some drugs of different categories are approved and prescribed to the patients and some others are still under investigation and have gone through clinical trials. Conclusion: As no specific treatment or drugs for this disease have been developed till the date; therefore, social distancing, home quarantine, and proper healthy lifestyle management are the best current short-term options to avoid further spread of this pervasive virus.

Authors

Shamabaditya Goswami

Department of Pharmacy, NIMS Institute of Pharmacy, NIMS University, Jaipur, Rajasthan, India.

Nikita Pal

Department of Pharmacy, NIMS Institute of Pharmacy, NIMS University, Jaipur, Rajasthan, India.

Kushal Nath Mishra

Department of Chemistry, ITM, GIDA, Gorakhpur, India.

Prashant Singh

Department of Pharmacy, NIMS Institute of Pharmacy, NIMS University, Jaipur, Rajasthan, India.

Zahra Chegini

Social Determinants of Health Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.

Ravindra Pal Singh

Department of Pharmacy, NIMS Institute of Pharmacy, NIMS University, Jaipur, Rajasthan, India.

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