The Prevalence of HBV and HCV Infection in HIV Positive Patients in North of Iran
Publish place: Research in Molecular Medicine، Vol: 5، Issue: 4
Publish Year: 1396
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_REMJ-5-4_007
تاریخ نمایه سازی: 22 دی 1402
Abstract:
Background: HIV infected persons are also at risk for Infection with other pathogens, like Hepatitis B virus (HBV) and Hepatitis C virus (HCV). One of the main steps in the planning of treatment and prevention is the study of the HIV positive population who have HBV and/or HCV infection.
The objective of this study was to determine the prevalence of HIV and Hepatitis B and C dual infection in north of Iran
Materials and methods: Blood samples were collected into EDTA containing tubes by sterile syringes and needles from ۸۳ HIV positive patients which were previously confirmed by Real-time Polymerase chain reaction in the HIV center of the north of IRAN. A structured questionnaire was used to obtain socio-demographic data from participants. Samples were screened for Hepatitis B surface antigen (HBsAg) and anti-HCV antibody. All non-reactive samples were recorded as negative.
Results: Out of the ۸۳ patients, ۵۰(۶۰%) were male and ۳۳ (۴۰%) were female. Positive hepatitis C antibody was found in ۲۸ (۳۳%) and positive hepatitis B surface antigen was present in ۱۵ (۱۸%) of patients. The frequency of all these three viruses co-infection was ۷ (۸%).
Conclusion: Seroprevalence of HCV and HIV co-infection was high and it was strongly related to mutual ways of acquisition.
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Authors
Mehrnaz Bakhti
Student research committee, faculty of Medicine, Sari, Mazandaran, Iran
Mohammadreza Haghshenas
Department of microbiology and immunology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Mazandaran, Iran
Reza Valadan
Molecular and Cell Biology Research center, Department of Immunology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Mazandaran, Iran
Mehdi Rabie Rudsari
HIV lab, Mazandaran University of Medical Sciences, Sari, Mazandaran, Iran
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