Natural Radioactivity of Tobacco and Its Role in Cancer Development
Publish place: Tobacco and Health، Vol: 2، Issue: 3
Publish Year: 1402
Type: Journal paper
Language: English
View: 161
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Document National Code:
JR_THJ-2-3_002
Index date: 22 January 2024
Natural Radioactivity of Tobacco and Its Role in Cancer Development abstract
Background: Tobacco use has remained a significant public health challenge worldwide dueto its strong association with various cancers. One of the little-known factors contributingto tobacco-related cancers is the presence of naturally occurring radioactive substances intobacco leaves. These naturally occurring radionuclides, such as radium-226, actinium-228,bismuth-214, and radium-228, originate from soil and fertilizers used in tobacco growing.Materials and Methods: In this review study, articles were collected from Medline, PubMed,Scopus, and Google Scholar search engines using keywords: “natural radioactivity,” “tobacco,”“cancer development,” “cigarette,” “smoking,” “cancer,” “carcinogenesis,” “radioresistance,”and “radiotherapy.” Articles were searched without a time limit. The inclusion criteria werearticles written in English and having full-text availability.Results: The studies demonstrate a strong correlation between smoking and side effects ofcancer treatment. These effects are not limited to specific cancer types but have been observedacross various malignancies and therapies.Conclusion: The carcinogenic mechanism of tobacco is very diverse and complex, involvingboth chemical and radiobiological factors. Understanding these mechanisms can help developsensitive methods to identify signature carcinogens in tobacco, facilitating effective andtargeted epidemiological studies.
Natural Radioactivity of Tobacco and Its Role in Cancer Development Keywords:
Natural Radioactivity of Tobacco and Its Role in Cancer Development authors
Mohammad Haghparast
of Radiology, Tobacco and Health Research Center, Faculty of Para Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran