Determinants of Serum Vitamin D level; A Data Mining Approach

Publish Year: 1402
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:

JR_JCTM-11-3_003

تاریخ نمایه سازی: 8 بهمن 1402

Abstract:

Introduction:  Serum vitamin D levels are related to a wide spectrum of factors including low sunlight exposure, high oxidative stress, low physical activity and sleep disorders. In this paper we are going to investigate the most crucial parameters associated with serum vitamin D levels in survey of ultraviolet intake by nutritional approach (SUVINA) study with a data mining approach.Material and Methods: Data including demographic, anthropometric, clinical and laboratory information were extracted from the SUVINA dataset comprising ۲۸۹ subjects who were enrolled into our study. The XGBoost algorithm was used to define the most important features related to vitamin D level in our population.Results: Applying XGBoost modeling for vitamin D level showed that the presented scheme can determine the most important determinants of serum vitamin D level with an accuracy of ۹۱%. Pro-oxidant anti-oxidant balance (PAB), body fat percentage, physical activity level (PAL), age, restless leg syndrome (RLS), and dietary inflammatory index (DII) density were the most important variables correlated with vitamin D deficiency.Conclusion: Using XGBoost and with an accuracy of more than ۹۰%, we showed that the six most important risk factors for vitamin D deficiency are PAB, PAL, age, body fat percentage, RLS and DII density, respectively.

Authors

Zahra Amiri

Department of Pure Mathematics, Center of Excellence in Analysis on Algebraic Structures (CEAAS), Ferdowsi University of Mashhad, P.O. Box ۱۱۵۹, Mashhad ۹۱۷۷۵, Iran.

Fahimeh Moafian

Department of Pure Mathematics, Center of Excellence in Analysis on Algebraic Structures (CEAAS), Ferdowsi University of Mashhad, P.O. Box ۱۱۵۹, Mashhad ۹۱۷۷۵, Iran.

Payam Sharifan

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Elahe Hasanzadeh

Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Zahra Khorasanchi

Department of Nutrition, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Moniba Bijari

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Maryam Mohammadi Bajgiran

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Sara saffar soflaei

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Susan Darroudi

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Hamideh Ghazizadeh

International UNESCO center for Health Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

fatemeh rouhi

Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Fatemeh Mohseni nik

Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Maryam Tayefi

Norwegian Center for E-Health Research, University Hospital of North Norway, Tromsø, Norway.

Samira roohi

Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Ayad Noor

Department of Biology, Faculty of Sciences, Mashhad Branch, Islamic Azad University, Mashhad, Iran.

Abdullah Al yakobi

Department of Biology, Faculty of Sciences, Mashhad Branch, Islamic Azad University, Mashhad, Iran.

Mohammed Hadi Lafta Alboresha

Department of Biology, Faculty of Sciences, Mashhad Branch, Islamic Azad University, Mashhad, Iran.

Gordon A. Ferns

Division of Medical Education, Brighton & Sussex Medical School, Falmer, Brighton, Sussex, UK.

Habibollah Esmaily

Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Majid Ghayour-Mobarhan

International UNESCO center for Health Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

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