A Sensitive Electrochemical Sensor for Determination of Imipramine in Urine Sample Using Carbon Ionic Liquid Electrode Modified With Montomorillonite Nanoclay

We used an effective electrochemical sensor for the determination of imipramine at pH ۷.۲ using a carbon nanocomposite electrode. The electrode has been designed by incorporation of montmorillonite nanoclay into the carbon ionic liquid electrode. The high sensitivity of ۱.۷۱۴ μA (μM)-۱, two linear calibration ranges of ۰.۱–۲ μM and ۲-۴۰ μM, and detection limit of ۱۹ nM were achieved. The relative standard deviations (RSDs) were ۲.۷۳% (n=۷, ۲ μM), ۲.۹۷% (n=۴, ۲ μM), respectively. Thus, this modified electrode was further applied to the determination of imipramine in urine sample.

Keywords:

Carbon ionic liquid electrode , electrochemical sensor , Imipramine , Montomorillonite Nanoclay