The Effect of Aerobic Exercise on Homocysteine, C- Reactive Protein and Lipid Profile in Active and Inactive Men

Publish Year: 1397
نوع سند: مقاله ژورنالی
زبان: English
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JR_RHCA-4-4_004

تاریخ نمایه سازی: 24 بهمن 1402

Abstract:

Introduction: A number of studies have reported that regular aerobic exercises can improve cardiovascular biomarkers such as homocysteine, C- reactive protein and lipid profile. The purpose of this study was to investigate the effect of ۴ weeks of aerobic exercise on homocysteine, C- reactive protein and lipid profile in active and inactive men. Methods: in this quasi-experimental study, ۲۶ active (n = ۱۳) and inactive (n = ۱۳) students aged (۱۸- ۲۳) years old participated voluntarily. All subject performed aerobic exercises for ۴ weeks, ۳ sessions per week and ۶۰ minutes with intensity of ۶۰- ۷۵ % of maximum heart rate reserve per session. Blood sample was taken in the pretest and ۲۴ hours after the last aerobic exercise session in the post- test. Independent sample t- test and paired sample t- test were used to analyze the data (p≤۰.۰۵). Results: Serum levels of homocysteine (P = ۰.۰۰۱) and low density lipoprotein cholesterol to high density lipoprotein cholesterol (P = ۰.۰۰۳) significantly decreased in the active group compared to the inactive group. However, there were no significant difference in the changes of C-reactive protein (P = ۰.۱۲), low density lipoprotein cholesterol (P = ۰.۵۶), triglyceride (P = ۰.۲۴), total cholesterol (P = ۰.۲۱), total cholesterol to high density lipoprotein (P = ۰.۵۲) and triglyceride to high density lipoprotein (P = ۰.۲۶), between active and inactive group. Conclusion: It appears that serum levels of homocysteine reduced further after four weeks of exercise in active subjects in comparison with inactive subjects. However, the improvement in the serum levels of C-reactive protein and lipid profiles after four weeks of exercise training were the same in both active and inactive individuals.

Authors

Mehrdad Fathi

Department of Sport Physiology, Ferdowsi University of Mashhad, Mashhad, Iran

Elham Pouryamehr

Department of Sport Physiology, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran

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