Compatibility of Clinical and Histopathological Diagnoses of Common Mucocutaneous Lesions in Hamadan University of Medical Sciences

Background: Many oral mucocutaneous lesions have quite similar clinical manifestation. Thus, histopathological assessment plays a pivotal role in the definite diagnosis of these lesions. This study aimed to evaluate the compatibility rate of clinical and histopathological diagnoses in our university hospitals and clinics. Methods: In this retrospective descriptive study, we evaluated the medical records of 168 patients who presented to the departments of oral and general pathology of Hamadan University from 1996 to 2014 with oral mucocutaneous lesions. Patients’ data were retrieved from their medical records which included baseline demographic data, lesion characteristics, primary clinical diagnosis, and definite histopathological diagnosis. Statistical analyses were performed using SPSS version 16.0. Results: Lichen planus was the most prevalent oral lesion in our study. The highest rate of agreement between the clinical and histopathological diagnoses was also noted for lichen planus. No agreement was noted for pemphigoid. Conclusions: Both clinical examination and histopathological analysis are required for correct and definite diagnosis of mucocutaneous lesions.