Several Risk Factors Associated with Cardiovascular Disease Event: Results from The Population-based MASHAD Cohort Study

Publish Year: 1402
نوع سند: مقاله ژورنالی
زبان: English
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JR_JCTM-11-4_002

تاریخ نمایه سازی: 29 بهمن 1402

Abstract:

Introduction: Cardiovascular disease (CVD) is the leading cause of mortality and one of the main challenges for health systems worldwide. In this study, we aimed to evaluate the association of socio-demographic, lifestyle, psychological and anthropometric factors and underlying diseases such as hypertension (HTN), diabetes mellitus (DM) and metabolic syndrome (MS) with CVD risk among a subpopulation of Iranian adults.Methods: In this prospective study, a total of ۲۳۵ CVD patients along with ۸۴۰۵ healthy and non-symptomatic individuals who participated in MASHAD cohort study were enrolled. CVD diagnosis was performed by taking electrocardiogram (ECG) and medical history and performing physical examination for each participant. Health and lifestyle questionnaires, the Beck’s anxiety inventory (BAI), Beck’s depression inventory (BDI) and the James and Schofield human energy requirements equations were completed for all participants. Anthropometric measurements were also recorded for all subjects. All statistical analyses including chi-square and student independent T-test were performed using SPSS ۱۶.۰ software (SPSS Inc., Chicago, IL, USA) at a significant level of ۰.۰۵.Results: We found that there were significant associations between CVD risk and age, body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR), diabetes mellitus (DM) and family history (FH) of CVD in both genders; though, there was a significant negative correlation between physical activity level (PAL) and risk of CVD among men and women. Also hypertension (HTN), metabolic syndrome (MS), depression and anxiety were positively and higher education level was negatively associated with CVD events only in females. While, waist-to-hip ratio (WHR) was an independent predictor of CVD among males (P-value< ۰.۰۵).Conclusion: There are several modifiable and non-modifiable risk factors that are independently considered as CVD predictors among the MASHAD study population. It is recommended to prioritize the lifestyle modification, development of local risk calculators and gender-related stratified strategies in order to prevent and manage CVD among the Iranian population.

Authors

Zahra Asadi

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Hamideh Ghazizadeh

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Mahdiyeh Yaghooti-Khorasani

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Moniba Bijari

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Hamed Khedmatgozar

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Ali Ebrahimi Dabagh

Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.

Mohammad Amin Mohammadi

Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.

Mohammad Reza Fazl Mashhadi

Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.

Shadi Kadkhoda-Ahmadi

Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.

Sara Moazedi

Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.

Arezoo Rastegar-Moghadam

Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.

Reza Zare-Feyzabadi

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Mohammad Mirzaei

Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.

Susan Darroudi

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Afsane Bahrami

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

maryam Tayefi

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Mohsen Mouhebati

Cardiovascular Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Alireza Heidari Bakavoli

Cardiovascular Research Center, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Gordon A. Ferns

Brighton & Sussex Medical School, Division of Medical Education, Falmer, Brighton, Sussex BN۱ ۹PH, UK.

Habibollah Esmaily

ocial Determinants of Health Research, Center, Mashhad University of Medical Sciences, Mashhad, Iran.

Majid Ghayour-Mobarhan

International UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

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