Application of WHONET in the Analysis of Pseudomonas aeruginosa Resistance to Imipenem and Meropenem
Publish place: Iranian Journal of Medical Microbiology، Vol: 17، Issue: 5
Publish Year: 1402
نوع سند: مقاله ژورنالی
زبان: English
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JR_IJMM-17-5_011
تاریخ نمایه سازی: 30 بهمن 1402
Abstract:
Background and Aim: WHONET software is a database for analyzing microbiology data, specifically antibiotic resistance patterns. Pseudomonas aeruginosa is a significant agent of nosocomial infections and has been identified as a critical priority by the World Health Organization (WHO). The aim of this study was to monitor the resistance patterns of imipenem and meropenem over one year (February ۲۰۲۲-February ۲۰۲۳) using WHONET software ۲۰۲۲.
Materials and Methods: A total of ۹۵ P. aeruginosa isolates were obtained from Kowsar Hospital in Sanandaj, Iran. After verification through biochemical tests and ۱۶sRNA PCR, an antibiogram test was performed for each isolate based on The Clinical & Laboratory Standards Institute (CLSI) guidelines. Data were analyzed using WHONET ۲۰۲۲.
Results & Conclusion: Pseudomonas aeruginosa isolates were obtained from ۴۴ females and ۵۱ males. Of all isolates, the WHONET analysis showed that resistance to imipenem and meropenem was ۸۷.۴% and ۶۴.۲%, respectively. The WHONET database can be an appropriate software for analyzing and monitoring bacterial susceptibility and resistance, especially for critical priority bugs such as P. aeruginosa.
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Authors
Rawezh Othman Ahmad
Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran
Amjad Ahmadi
Department of Microbiology, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
Nasrin Bahmani
Zoonoses Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran
Arezou Taherpour
Department of Microbiology, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran
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