The Optimizing Process of the Blood Coagulation Powder Composition With Response Surface Methodology
Publish place: Computational Sciences and Engineering، Vol: 2، Issue: 2
Publish Year: 1401
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_CSE-2-2_016
تاریخ نمایه سازی: 5 اسفند 1402
Abstract:
This study focuses on optimizing process of the blood coagulation powder composition with response surface methodology. For this purpose, optimizing the synthesis conditions of powder composition, the response surface methodology (RSM) was used by Box-Behnken design (BBD). The variables of this method were sodium alginate (A) and zinc oxide nanoparticles (B), prepared in combination with a fixed percentage of shell powder and measured for different reactions. results showed that according to the response surface methodology, which is the most optimal case, to introduce this method as a suitable suggestion for this kind of problem in the applications of vascular surgeries, burns, etc., and direct to future pre-clinic and clinical studies.
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Authors
Reza Zarei
Department of Statistics, Faculty of Mathematical Sciences, University of Guilan, Rasht, Iran.
Seyyedeh Sahra Mirmasoudi
Burn and Regenerative Medicine Research center, Guilan University of Medical Sciences, Rasht
Alireza Feizkhah
Department of Medical Physics, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
Zahra Pourmohammadi Bejarpasi
Burn and Regenerative Medicine Research center, Guilan University of Medical Sciences, Rasht, Iran
Mohsen Shahrousvand
Caspian Faculty of Engineering, College of Engineering, University of Tehran, Tehran, Iran
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