Detection of Biologically Active Compounds in Eriobotrya japonica L. Seeds Extract and Determination of Their Effectiveness Against Dermatophytes

The antifungal activity of Eriobotrya japonica L. seeds extract obtained from Baghdad was evaluated against nine clinical fungi isolates of dermatopytes (T. rubrum, T. mentographytes, M. canis, T. verrucosum, T. quinckeanum, Epidermophyton, T. simii, T. interdigitale and Fusarium). The results presented in this work demonstrated that the seeds extract showed a significant effect against dermatophytes at 300 mg/ml concentration, with percentage inhibition growth ranging from 100% to 96.56%, compared to concentrations at 150 and 75 mg/ml, with percentage inhibition growth ranging from 97.27% to 86.66% and from 93.66% to 79.84% respectively. The end results of GC-MS analysis indicated that the ethanol seeds extract of loquat have a lot of active chemical compounds, including twenty-five phytoconstituent compounds, that are distinguished in the extract of seeds with E. japonica L. In addition, the high area % revealed in each extracts were: Propylene glycol monooleate 5.03%, D-Mannitol or DL-Glucitol 5.67%, Beta-sitosterol 5.70%, n-Hexadecanoic acid 14.53% and 9,12-Octadecadienoic acid (Z,Z)- 22.85%.

Detection of Biologically Active Compounds in Eriobotrya japonica L. Seeds Extract and Determination of Their Effectiveness Against Dermatophytes Keywords:

Eriobotrya japonica , Seeds , Dermatopytes , Ethanol extract , Antifungal