Investigating the effect of ۱۲ weeks of aerobic exercise on fasting glucose and several serum indicators of cardiovascular disease in women with type ۲ diabetes

Purpose: Type ۲ diabetes is one of the most important metabolic disorders that different societies are facing with increasing prevalence. Aerobic exercises are a common type of exercise that reduces the levels of triglycerides and low-density lipoproteins and regulates blood pressure. The purpose of the research is to investigate the effect of ۱۲ weeks of aerobic exercise on fasting glucose and several serum indicators of cardiovascular disease, in women with type ۲ diabetes. Methods: In ۲۰۲۳, ۲۰ women who referred to the Hamadan Diabetes Association voluntarily participated as subjects in this research and were randomly assigned to aerobic (۱۰ people) and control (۱۰ people) groups. The exercise program of the aerobic group included ۳ running sessions per week with an intensity of ۶۰-۷۰% of the maximum heart rate for ۱۲ weeks. In order to measure fasting blood glucose, glycosylated hemoglobin (HbA۱c) and lipid profile [low-density lipoprotein (LDL-c), triglycerides (TG), High-density lipoprotein (HDL-c)], blood sampling was done before and after ۱۲ weeks of exercise program. SPSS software and Kologrov Smirnov and Student's t test were used to check and analyze the data. Results: The results indicated that after ۱۲ weeks of aerobic exercise, HbA۱c (P=۰/۰۲۷), LDL-c (P=۰/۰۱۲) and fasting blood glucose (P=۰/۰۴۳) decreased significantly in the aerobic group. But no significant changes were observed in HDL-c and BMI. Conclusion: The results of this research showed that performing aerobic exercises leads to a decrease in HbA۱c, fasting blood glucose and improvement in lipid profile, so it can probably be a useful way of treatment and prevention of cardiovascular diseases in type ۲ diabetic patients.

Keywords:

cardiovascular disease , diabetes , aerobic activity , HbA۱c