In vivo lavicidal effects of ginger (Zingiber officinale) powder on pigs artificially infected with gastointestinal nematode larvae

Anthelminthic resistance due to the mismanagement of conventional drugs remains a major constraint in eradicating gastrointestinal parasites, hence the need for alternatives drugs which are more ecofriendly and affordable. This paper evaluated the In vivo lavicidal effect of ginger Zingiber officinale in pigs experimentally infected with association of Strongyloides ransomi, Hyostrongylus rubidus, Trichostrongylus colubriformis and Globocephalus urosubulatus L۳ larvae. The experiment, conducted at the teaching and research farm of the University of Dschang consisted of ۱۲ pigs divided into two treatment groups (the control group, T۰ and the treated group, T۱). The control group (T۰) was infected with ۲۶۵۰L۳ larvae and was not treated. The treated group (T۱) was infected with ۲۶۵۰L۳ larvae and treated with ۵۰۰g of ginger powder. Six weeks after infection, faecal samples were collected directly from the rectum of all the pigs to determine the presence of eggs, the faecal egg count, and also to carry out larval culture. Ginger powder reduced the shedding of eggs in Strongyloides ransomi and strongylid parasites by ۱۲.۹% and ۵۳.۴% respectively. The mean log۱۰ EPG in the untreated group was also significantly higher than that in the treated group. The L۳ larvae obtained after larval culture were of the same species as those used to infect the pigs. The larvae cultures showed that ginger reduced the shedding of eggs in Strongyloides ransomi, Hyostrongylus rubidus, Trichostrongylus colubriformis and Globocephalus urosubulatus by ۳۲.۹۷%, ۱۸.۸۴%, ۹.۴۶%, and ۱۷.۴۱% respectively. The mean L۳ nematode larvae cultured in the treated group was significantly lower (p<۰.۰۵) than in the untreated group for Strongyloides ransomi and Trichostrongylus colubriformis. In conclusion, ginger powder reduced the shedding of eggs of all the studied nematode species, and the eggs shed were viable. In order to definitely conclude on the effect of ginger powder on these nematodes in pigs, further studies on the duration of treatment and the active compound in ginger powder are required.Anthelminthic resistance due to the mismanagement of conventional drugs remains a major constraint in eradicating gastrointestinal parasites, hence the need for alternatives drugs which are more ecofriendly and affordable. This paper evaluated the In vivo lavicidal effect of ginger Zingiber officinale in pigs experimentally infected with association of Strongyloides ransomi, Hyostrongylus rubidus, Trichostrongylus colubriformis and Globocephalus urosubulatus L۳ larvae. The experiment, conducted at the teaching and research farm of the University of Dschang consisted of ۱۲ pigs divided into two treatment groups (the control group, T۰ and the treated group, T۱). The control group (T۰) was infected with ۲۶۵۰L۳ larvae and was not treated. The treated group (T۱) was infected with ۲۶۵۰L۳ larvae and treated with ۵۰۰g of ginger powder. Six weeks after infection, faecal samples were collected directly from the rectum of all the pigs to determine the presence of eggs, the faecal egg count, and also to carry out larval culture. Ginger powder reduced the shedding of eggs in Strongyloides ransomi and strongylid parasites by ۱۲.۹% and ۵۳.۴% respectively. The mean log۱۰ EPG in the untreated group was also significantly higher than that in the treated group. The L۳ larvae obtained after larval culture were of the same species as those used to infect the pigs. The larvae cultures showed that ginger reduced the shedding of eggs in Strongyloides ransomi, Hyostrongylus rubidus, Trichostrongylus colubriformis and Globocephalus urosubulatus by ۳۲.۹۷%, ۱۸.۸۴%, ۹.۴۶%, and ۱۷.۴۱% respectively. The mean L۳ nematode larvae cultured in the treated group was significantly lower (p<۰.۰۵) than in the untreated group for Strongyloides ransomi and Trichostrongylus colubriformis. In conclusion, ginger powder reduced the shedding of eggs of all the studied nematode species, and the eggs shed were viable. In order to definitely conclude on the effect of ginger powder on these nematodes in pigs, further studies on the duration of treatment and the active compound in ginger powder are required.

Keywords:

Anthelminthic resistance , Globocephalus urosubulatus , Hyostrongylus rubidus , Strongyloides ransomi , Trichostrongylus colubriformis