Assessment of Frequency and antibiotic resistance pattern of Acinetobacter spp. isolated from traumatic patients in Shahid Rajaee Hospital in Shiraz

Acinetobacter resistant strains have caused medical problems throughout the world. The aim of this study was to evaluate the frequency and pattern of antibiotic resistance of Acinetobacter species isolated from traumatic patients in Shahid Rajaee hospital in Shiraz. In this study, ۷۹۴ samples were isolated from patients in Shahid Rajaee Hospital. Identification of Acinetobacter was done by biochemical tests and PCR method. Multi-drug resistant (MDR) Acinetobacter were determined using gentamicin, piperacillin, meropenem, colistin, trimethoprim, ciprofloxacin, imipenem, ampicillin, and chloramphenicol antibiotics. In this study, ۲۴۸ samples of Acinetobacter isolates were identified by molecular and biochemical methods from patients. All of which were isolates of MDR Acinetobacter. The highest percentage of Acinetobacter isolates was reported for upper respiratory tract samples and the lowest for urinary tract. The highest percentage of infection was related to Acinetobacter co-infection with one bacterium in patients aged ۴۵ to ۸۷ years old. As the number of male patients with accident trauma was more than women, the percentage is higher in men. The percentage of patients with Acinetobacter infection in ICUs was higher than in other sections. These results show the evidence of necessity to examine the transmission ways and the increasing incidence of hospital infections.

Keywords:

Nosocomial Infection , Acinetobacter , Traumatic patients , Muti Drug Resistance , Antibiotic resistance