The effects of opium addicyion on testosterone and gonadotropins in addicted men
Publish Year: 1374
نوع سند: مقاله ژورنالی
زبان: Persian
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شناسه ملی سند علمی:
JR_JKMU-2-4_001
تاریخ نمایه سازی: 19 اسفند 1402
Abstract:
the precise pharmacological of chronic use of opium on serum level of gonadotropins and male sex hormones are not studied extensively.this study was performed to investigate the changes in these parameters is opium addicted men.the blood samples of ۴۶ opium addicts and ۳۹ normal men were taken ,and the testosterone ,LH and FSH levels in serum were measured by radioimmunoassay (RID) technique using a LKB gamma counter.the results of this study showed that the serum testosterone in opium addicts were decreased significantly compared to the controls(p<۰.۰۱).this reduction was directly proportional to the duration of opium usage.the LH and FSH levels in opium addicts showed also significant reduction compared to the controls(p<۰.۰۱ & p<۰.۰۵ respectively). in summary the chronic use of opium can cause significant changes in endorcine reproductive functions including hypothalamic- hy pophyseal gonadal axis.
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Authors
GH.R Sepehri
Assistant professor
A GHolam hoseiniyan
Assistant professor
H Hejazian
Instructor
SH Dabiri
Assistant professor