Vitamin C Intervention in Type ۲ Diabetes Mellitus: A Comprehensive Analysis of Lipid Profile and Glycemic Parameters
Publish place: Journal of Medicinal and Chemical Sciences، Vol: 7، Issue: 5
Publish Year: 1403
نوع سند: مقاله ژورنالی
زبان: English
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JR_JMCH-7-5_010
تاریخ نمایه سازی: 18 فروردین 1403
Abstract:
Worldwide many people are affected by Type ۲ Diabetes mellitus (DM). This study aimed to assess how lipid and glycemic parameters are affected by ascorbic acid in adult population suffering from type ۲ DM. Two groups were formed one was control group with ۱۰۳ patients and other was treatment group with ۱۰۳ patients. The intervention group was administered ۵۰۰ mg of vitamin C three times a day in conjunction with oral hypoglycemic medications for duration of three months. Fasting blood sugar, random blood sugar, glycosylated hemoglobin, total cholesterol, serum triglycerides, high density lipoproteins cholesterol, and low density lipoproteins cholesterol tests were conducted at start of study and again after three months. Means were compared between control and treatment groups. Correlation and regression analysis between vitamin C and laboratory parameters were also performed. Lipid profile, fasting blood sugar, and random blood sugar were affected significantly by ascorbic acid and there was significant correlation between them. However, regression analysis revealed that, except for high-density lipoprotein cholesterol, there was no statistical significance in the impact on the overall lipid profile. The current study's conclusion suggests that administering vitamin C as supplementary therapy alongside anti-diabetic medications, over an extended period and in divided doses, can influence glycemic parameters and lipids.
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Authors
Shabzain Ishrat
Department of Pharmacology, Shahida Islam Medical College, Lodhran, Pakistan
Adeel Zafar
Department of Pathology, Shahida Islam Medical College, Lodhran, Pakistan
Farheen Hameed
Department of Pharmacology, Shahida Islam Medical College, Lodhran, Pakistan
Sibgha Bashir
Department of Pathology, Shahida Islam Medical College, Lodhran, Pakistan
Sara Khan
Department of Pathology, CMH Institute of Medical Sciences, Bahawalpur, Pakistan
Rizwan Hafeez
Department of Medicine, Shahida Islam Medical College, Lodhran, Pakistan
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