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Voltammetric Sensor for Acyclovir Determination Based on MoSe2/rGO Nanocomposite Modified Electrode

Publish Year: 1403
Type: Journal paper
Language: English
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Document National Code:

JR_CHM-8-5_001

Index date: 8 June 2024

Voltammetric Sensor for Acyclovir Determination Based on MoSe2/rGO Nanocomposite Modified Electrode abstract

In this study, MoSe2/rGO nanocomposite modified screen printed graphite electrode (SPGE) was designed for acyclovir (ACV) determination. The electrochemical investigation and measurement of ACV were performed by applying some voltammetric techniques and chronoamperometry. After modification of SPGE, the enhancement of the voltammetric response and the reduction of overpotential of ACV confirmed the good electrocatalytic ability of MoSe2/rGO/SPGE sensor towards the ACV oxidation. The voltammetric method (differential pulse voltammetry (DPV)) was used to investigate the determination ability of MoSe2/rGO nanocomposite/SPGE towards ACV determination under the optimum parameters and conditions. The MoSe2/rGO/SPGE sensor indicated appreciable sensing ability towards ACV, with an optimal linear response from 0.03-190.0 µM and a limit of detection (LOD) of 0.01 µM. More importantly, the practical applicability of the designed sensor was confirmed in the ACV quantification in ACV tablet and urine samples, showing its potential application for real sample analysis.

Voltammetric Sensor for Acyclovir Determination Based on MoSe2/rGO Nanocomposite Modified Electrode Keywords:

Screen printed graphite electrode , Electrochemical sensor , MoSe2/rGO nanocomposite , acyclovir

Voltammetric Sensor for Acyclovir Determination Based on MoSe2/rGO Nanocomposite Modified Electrode authors

Somayeh Tajik

Research Center of Tropical and Infectious Diseases, Kerman University of Medical Sciences, Kerman P.O. Box ۷۶۱۶۹-۱۳۵۵۵, Iran

Fariba Garkani Nejad

Environment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran

Reza Zaimbashi

Environment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran

Hadi Beitollai

Environment Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced Technology, Kerman, Iran

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