Three-Component Synthesis of Bis(indolyl)methane with Sulfanilic Acid as an Efficient Catalyst
Publish place: Eurasian Journal of Science and Technology، Vol: 4، Issue: 4
Publish Year: 1403
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_EJST-4-4_004
تاریخ نمایه سازی: 27 خرداد 1403
Abstract:
The biological activities and therapeutic qualities of indoles as well as their derivatives have garnered significant attention. I n this study, the solid acidic organocatalyst (sulfanilic acid) was examined for the synthesis of derivatives of bis(indolyl)methanes (BIMs) at ambient temperature and in water and ethanol as solvent. BIMs was prepared and characterized by appearance, TLC, FT-IR, and melting point and were further supported by CHNS analysis. The approach has a lot of advantages, including a clean reaction, operational simplicity, a simple experimental work-up process, waste minimization, non-toxicity, quicker reaction times, and high yields of the compounds.
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Authors
Hoda Banari
Department of Chemistry, Damghan University, Damghan, Semnan, Iran
Hamzeh Kiyani
Department of Chemistry, Faculty of Science, Shahrekord University, Shahrekord, Iran
Alireza Pourali
Department of Chemistry, Damghan University, Damghan, Semnan, Iran
Parvin Hajiabbastabar Amiri
Department of Chemistry, Damghan University, Damghan, Semnan, Iran
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