An Overview of the Role of Mmicrobiomes in the Severity of Colorectal Cancer
Publish place: Personalized Medicine Journal، Vol: 9، Issue: 34
Publish Year: 1403
نوع سند: مقاله ژورنالی
زبان: English
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شناسه ملی سند علمی:
JR_PMJ-9-34_004
تاریخ نمایه سازی: 6 شهریور 1403
Abstract:
Microbiome means microbes coexisting with the host, regardless of the species, in a part of the body of an organism called microbiome. Nowadays, changes in gut microbiota are considered as a potential therapeutic approach for the prevention or treatment of colorectal cancer (CRC).Studies have shown that dietary habits and lifestyle play a role in modulating the gut microbiota.Intestinal microbiota plays a role in converting food components into oncometabolites. Some studies showed that Shigella, Citrobacter and Salmonella bacteria are more abundant in the early stages of cancer compared to healthy people. The aim of this study is to review the role of microbiomes in the development of colorectal cancer and the metabolites produced by microbiomes in the development of colorectal cancer.
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Authors
Ramesh Ranjbar
Department of Genetics, Faculty of Basic Sciences, Shahrekord Islamic Azad University, Shahrekord, Iran