Comparative Phytochemical Study of Artemisia sp. in the Middle East: A Focus on Antimicrobial Activities and GC-MS Analysis in A. absinthium L. Jazan, KSA and A. herba-alba Asso Sinai, EGY

This study deals with the potential antimicrobial activity of Artemisia absinthium L. (from Saudi Arabia) and Artemisia herba-alba Asso. (from Egypt) extracts by using variety of solvents. The pathogenic microorganisms; Candida albicans, Cronobacter sakazakii, Enterococcus faecalis and Salmonella enterica, were manipulated. The MICs recorded different affinities for each solvent. The MBC and MFC were also determined. The chemical compositions of two plant species were determined by GC-MS analysis. A comparative study was conducted among Artemisia sp. belonging to the Middle East region. They are A. absinthium, A. abyssinica, A. annua, A. herba-alba, A. judaica, A. monosperma, A. scoparia, A. sieberi and A. vulgaris. The binary matrix included the chemical components of Artemisia sp. The phenogram and similarity matrix cleared the recent chemotaxonomic position of this genus in the Middle East. MIC values of both plant species were analyzed using the ANOVA test. Pearson correlation coefficients were calculated in the form of SLR curves. The two studied plant species were recommended as alternative natural antimicrobial inhibitor agents.

Comparative Phytochemical Study of Artemisia sp. in the Middle East: A Focus on Antimicrobial Activities and GC-MS Analysis in A. absinthium L. Jazan, KSA and A. herba-alba Asso Sinai, EGY Keywords:

Candida , Cronobacter , enterococcus , Salmonella , Chemotaxonomy , SARS-CoV-2 , phenogram , COVID , Binary matrix