Benzimidazolium Dihydrogen Phosphate: A Novel Green Catalyst for the Preparation of Pyrano[۲,۳-𝑑]pyrimidines and Pyrano[۳,۲-𝑐]chromenes in Aqueous Media

In this study, a novel benzimidazole-based Brönsted acidic ionic salt, benzimidazolium dihydrogen phosphate, was synthesized and characterized using Mass spectrometry, FT-IR and NMR spectroscopy, as well as ICP analysis. The salt demonstrated efficient catalytic properties and reusability in the production of pyrano[۲,۳-d]pyrimidine and pyrano[۳,۲-c]chromene derivatives. Noteworthy advantages of this approach include the minimal catalyst requirement, straightforward work-up process, brief reaction duration, high yields, and catalyst reusability for four consecutive uses without a significant decrease in efficiency.

Keywords:

Brönsted acidic organic salt , benzimidazolium dihydrogen phosphate , Pyrano[۲ , ۳-𝑑]pyrimidines , Pyrano[۳ , ۲-𝑐]chromenes , Aqueous media