The possible involvement of miR-34 in cancer treatment
Publish place: Tabari Biomedical Student Research Journal، Vol: 6، Issue: 4
Publish Year: 1403
Type: Journal paper
Language: English
View: 62
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Document National Code:
JR_TBSRJ-6-4_004
Index date: 3 December 2024
The possible involvement of miR-34 in cancer treatment abstract
Cancer is one of the major causes of morbidity and mortality worldwide, resulting from complex interactions between genetic, epigenetic and environmental factors. In the present study, the multifaceted nature of cancer, epidemiology, pathogenesis, and the complex role of genes and microRNAs in the development and progression of tumors have been investigated. We delved into the importance of oncogenes and tumor suppressor genes, especially the pivotal role of the p53 gene in cell cycle regulation and DNA repair mechanisms. In addition, in the current study, the therapeutic potential of microRNAs, especially miR-34, in overcoming chemotherapy resistance and Increasing the effectiveness of treatment has been discussed. By understanding these underlying mechanisms, we aim to provide insight into innovative cancer prevention and treatment strategies.
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The possible involvement of miR-34 in cancer treatment authors
Melika Izadpanah
tabriz university of medical sciences
Oyinkansola Adebomojo
Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, IN, USA. ۲. Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, IN, USA.
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